RDKit two component reaction issues
Hi I have a reaction enumeration where I am reacting a set of acids to 1 amine and have 2 issues:
The amine is reacting with esters as well as amines (I want to leave the esters in as a possible substituent)
I get an error or “A product molecule could not be sanitized successfully - skipping it”
In general I get all the right compounds out with a few reacting at the ester instead.